All of the above, I'm sure, though as others have said some are better than others. I correlate this more with online play as it's less logistics. I have had requests for booze and poppers in person. Poppers are definitely my preference as they don't last as long as the others. I'd take it way more slowly with the others, definitely agree with Maya about the time component, as well as alcohol being the worst. It's certainly the most dangerous!

I had one guy show me everything in the minibar and say he wanted to be "forced" to drink it all. When I asked about his standard drinking habits/threshold/limits, apparently he never drank, like ever. That would not have ended well! I'm all for pushing limits, but dude...